Custom Peptides
Cayman Chemical JWH 122 5-methylnaphthyl isomer, Purity: ≥98%, CAS: 1391052-02-0, 10 mg
Differs from JWH 122 in that the methyl group is attached to the naphthyl rings at the 5, rather than the 4, position; intended for forensic purposes
Cayman Chemical Aripiprazole N,N-dioxide, Purity: ≥90%, CAS: 573691-13-1, 10 mg
A metabolite of aripiprazole
Cayman Chemical Astragaloside II, Purity: ≥98%, CAS: 84676-89-1, 10 mg
A triterpene saponin with diverse biological activities; increases the phosphatase activity of CD45 in cell-free assays using pNPP or OMFP as substrates (EC50s = 9.23 and 5.37 µg/ml, respectively); inhibits replication of dengue virus serotypes 1 and 3 in infected Vero cells (MIC = 1.56 µg/ml for both); increases concanavalin A-induced proliferation of primary mouse splenocytes at 30 nM; inhibits autophagy and enhances apoptosis induced by cisplatin in SGC-7901 gastric cancer cells at 50 µM; prevents decreases in small intestine and colon length, as well as body weight, in a mouse model of TNBS-induced colitis at 10 mg/kg; decreases the urinary albumin-to-creatinine ratio and improves histopathological scores in a rat model of STZ-induced diabetic nephropathy at 3.2 and 6.4 mg/kg
Cayman Chemical 7α-hydroxy Dehydroepiandrosterone, Purity: ≥98%, CAS: 53-00-9, 10 mg
An active metabolite of dehydroepiandrosterone; formed from dehydroepiandrosterone via 7-hydroxylation by CYPs; increases antigen-induced production of anti-tetanus toxoid and anti-pertussis antigen IgGs in co-cultures of human tonsil-derived B and T cells at 1 µM; increases serum concentrations of anti-lysozyme IgG in mice at 6.25 mg/kg
Cayman Chemical bk-2C-B (hydrochloride), Purity: ≥98%, CAS: 2303508-66-7, 10 mg
A β-ketone analog of 2C-B; intended for forensic and research purposes
Cayman Chemical BMK methyl glycidate, Purity: ≥98% (mixture of cis/trans isomers), CAS: 80532-66-7, 10 mg
An analytical reference standard categorized as a precursor in the synthesis of phenylacetone; intended for research and forensic applications
Cayman Chemical Green CMFDA, Purity: ≥95%, CAS: 136832-63-8, 10 mg
A cell-permeable fluorescent probe that freely enters living cells, where it is transformed into a cell-impermeable, soluble, fluorescent compound; does not affect cell viability or proliferation and stably fluoresces for at least 72 hours, allowing for its use in cell tracking
Cayman Chemical 1-Stearoyl-2-Docosahexaenoyl-sn-glycero-3-PC, Purity: ≥95%, CAS: 59403-52-0, 10 mg
A phospholipid; has been used in the study of lipid membrane organization and dynamics; levels are decreased in the L5 anterior horn in a SOD1G93A transgenic mouse model of ALS at the terminal stage of disease
Cayman Chemical PolIumosIde 10mg
A phenylethanoid glycoside; scavenges DPPH and ABTS radicals (IC50s = 10.9 and 19.9 µM), as well as inhibits the activity of PKCα (IC50 = 24.4 µM), in cell-free assays); reduces LPS-induced production of TNF-α and IL-6 in RAW 264.7 cells from 12.5-100 µM; decreases glutamate-induced cytotoxicity in primary rat cortical neurons at 0.1, 1, or 10 µM
Cayman Chemical Thermopsine, Purity: ≥98%, CAS: 486-90-8, 10 mg
An alkaloid; reduces LPS-induced production of TNF-α in RAW 264.7 cells at 50 µM
Cayman Chemical NGB 2904 (hydrochloride), Purity: ≥98%, CAS: 189061-11-8, 10 mg
A selective dopamine D3 receptor antagonist (Ki = 1.4 nM); attenuates cocaine- and stress-induced reinstatement of drug-seeking behavior in rats
Cayman Chemical Naphthol AS-E Phosphate, Purity: ≥98%, CAS: 18228-17-6, 10 mg
An inhibitor of the protein-protein interaction between CREB and KIX domains; disrupts binding between CREB and the KIX domain of CBP (Ki = 50 µM); inhibits binding of Myb to the KIX domains of p300 and CBP (IC50s = 30 and 43 µM, respectively); inhibits CREB-dependent transcription in HEK293T cells (Ki = 10 µM); decreases the expression of Myb target genes and induces differentiation in HL-60, U937, and NB4 myeloid leukemia cells at 5 µM; inhibits proliferation of NCI-H1734 lung adenocarcinoma cells (IC50 = 6.89 µM)
Cayman Chemical Cephalomannine, Purity: ≥98%, CAS: 71610-00-9, 10 mg
A taxane diterpenoid; inhibits calcium-induced microtubule depolymerization in vitro; increases vincristine accumulation in multidrug-resistant 2780AD ovarian cancer cells
Cayman Chemical Soyasaponin II, Purity: ≥98%, CAS: 55319-36-3, 10 mg
A saponin with diverse biological activities; inhibits the proliferation of, and induces apoptosis in, HeLa cells from 100-400 mg/L; inhibits viral replication in cells infected with HSV-1, HCMV, or influenza virus (IC50s = 54, 104, and 88 µM, respectively); prevents the development of acute liver failure in a mouse model of LPS/D-galactosamine-induced acute liver injury at 5 mg/kg